Just when the Portuguese coach must have thought his fortune wasn't changing, Manchester United managed to inflict the home side's first home defeat in the Premier League since February.
The Palace manager's team dominated early justifiably opened the scoring via Jean-Philippe Mateta's second penalty attempt. However they failed to capitalize on their control and having failed to find the net at Selhurst, Amorim's team countered two times in quick succession from their summer signing and the English midfielder.
The match proved disappointing encounter finishing of a long week for the Palace boss, who witnessed the Senegalese international limp off with a worrying issue in the first period.
Ruben Amorim may have kept his feelings controlled when proceeding toward the dressing room directly following the final whistle.
Amorim had played down parallels involving both managers' game philosophy during preparation, although he acknowledged that Glasner's team "are just doing things better than us|aspects superior to ours|elements more effectively".
The reaction following the disappointing loss versus reduced Everton meant modifying the wide defenders, with Amad Diallo occupying the right wing with the full-back replaced Patrick Dorgu.
Amorim's team probably recognized a chance to benefit considering they enjoyed additional preparation time and nearly scored first after 43 seconds.
A lengthy throw-in caused chaos in the Palace area but somehow Dean Henderson produced a point-blank save at his goal line to prevent the midfielder.
The narrow escape served as a wake-up call for Palace post the lunchtime beginning that was scheduled by TV requirements.
Soon the chances started arriving frequently. Subsequent to squandered numerous attempts in midweek, it seemed like perhaps it wouldn't be Mateta's day after he sent efforts missing the goal in the initial phase.
However during a period when talks over the forward's renewal faced delays, Mateta stepped up who opened the scoring.
One more perfect ball from Wharton lured Leny Yoro into the challenge and, having just made superb interception to prevent the Spaniard, the young defender had to trip his compatriot within the 18-yard area.
Henderson re-emerged with head protection to block the sun from the low sun but he will be disappointed to have allowed United to draw equal post the break.
Glasner's team was unprepared by a quick Bruno Fernandes free-kick and Zirkzee was able to bring under control and pivot in one motion to produce a shot that flew into the net.
After enduring a chaotic situation where Zirkzee almost scored another time defensively, their situation enhanced shortly afterward as the Dutch attacker was brought down outside the penalty area by Marc Guéhi.
There was a moment's hesitation within the barrier when Fernandes rolled the free-kick to Mount enabling the Englishman to defeat the goalkeeper via a strong shot.
Without Sarr's pace to call on, Palace could barely muster another chance as United were able to complete a crucial victory that means United move above Palace into sixth place.
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